Gene name:
MAGED1 (PRO2292;PP2250;NRAGE) ;
Protein name:
Melanoma-associated antigen D1 ;
Alternative:
MAGE-D1 antigen ;MAGE tumor antigen CCF ;Neurotrophin receptor-interacting MAGE homolog ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with DLX5, DLX7 and MSX2 and forms homomultimers. Interacts with UNC5A (By similarity). Interacts with the p75 neurotrophin receptor.
Function:
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
Subcellular Location:
Cytoplasm
Cell membrane
Peripheral membrane protein
Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF.
Protein Attributes:
50:
MAQKMDCGAG | LLGFQAEASV | EDSALLMQTL | MEAIQISEAP | PTNQATAAAS |
100:
PQSSQPPTAN | EMADIQVSAA | AARPKSAFKV | QNATTKGPNG | VYDFSQAHNA |
150:
KDVPNTQPKA | AFKSQNATPK | GPNAAYDFSQ | AATTGELAAN | KSEMAFKAQN |
200:
ATTKVGPNAT | YNFSQSLNAN | DLANSRPKTP | FKAWNDTTKA | PTADTQTQNV |
250:
NQAKMATSQA | DIETDPGISE | PDGATAQTSA | DGSQAQNLES | RTIIRGKRTR |
300:
KINNLNVEEN | SSGDQRRAPL | AAGTWRSAPV | PVTTQNPPGA | PPNVLWQTPL |
350:
AWQNPSGWQN | QTARQTPPAR | QSPPARQTPP | AWQNPVAWQN | PVIWPNPVIW |
400:
QNPVIWPNPI | VWPGPVVWPN | PLAWQNPPGW | QTPPGWQTPP | GWQGPPDWQG |
450:
PPDWPLPPDW | PLPPDWPLPT | DWPLPPDWIP | ADWPIPPDWQ | NLRPSPNLRP |
500:
SPNSRASQNP | GAAQPRDVAL | LQERANKLVK | YLMLKDYTKV | PIKRSEMLRD |
550:
IIREYTDVYP | EIIERACFVL | EKKFGIQLKE | IDKEEHLYIL | ISTPESLAGI |
600:
LGTTKDTPKL | GLLLVILGVI | FMNGNRASEA | VLWEALRKMG | LRPGVRHPLL |
650:
GDLRKLLTYE | FVKQKYLDYR | RVPNSNPPEY | EFLWGLRSYH | ETSKMKVLRF |
700:
IAEVQKRDPR | DWTAQFMEAA | DEALDALDAA | AAEAEARAEA | RTRMGIGDEA |
750:
VSGPWSWDDI | EFELLTWDEE | GDFGDPWSRI | PFTFWARYHQ | NARSRFPQTF |
778:
AGPIIGPGGT | ASANFAANFG | AIGFFWVE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Rat
Mouse
ELISA Kit for Human Melanoma-associated antigen D1
ELISA Kit for Human Melanoma-associated antigen D1
ELISA Kit for Human Melanoma-associated antigen D1
ELISA Kit for Human Melanoma-associated antigen D1
CLIA Kit for Human Melanoma-associated antigen D1
CLIA Kit for Human Melanoma-associated antigen D1
CLIA Kit for Human Melanoma-associated antigen D1
CLIA Kit for Human Melanoma-associated antigen D1
Polyclonal Antibody for Human Melanoma-associated antigen D1
Polyclonal Antibody for Human Melanoma-associated antigen D1
Polyclonal Antibody for Human Melanoma-associated antigen D1
Polyclonal Antibody for Human Melanoma-associated antigen D1
Monoclonal Antibody for Human Melanoma-associated antigen D1
Monoclonal Antibody for Human Melanoma-associated antigen D1
Monoclonal Antibody for Human Melanoma-associated antigen D1
Monoclonal Antibody for Human Melanoma-associated antigen D1
Protein for Human Melanoma-associated antigen D1
Protein for Human Melanoma-associated antigen D1
Protein for Human Melanoma-associated antigen D1
Protein for Human Melanoma-associated antigen D1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 304-778
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Testis .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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